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Water-Insoluble Drug Formulation, Second Edition by Rong Liu

Water-Insoluble Drug Formulation, Second Edition Rong Liu ebook
Page: 688
Format: pdf
ISBN: 0849396441, 9780849396441
Publisher: CRC Press

€�These new compounds, like rocks, never dissolve in water.” It sounds so familiar to you, does it not? Tong, “Preformulation Aspects of Insoluble Compounds” in Water Insoluble Drug Formulation, Edited by R. Formulation features and clinical studies. In this technique, liquid medications of water insoluble drugs in non-volatile liquid vehicles can be converted into acceptably flowing and compressible powders. - Therapeutic category and anticipated dose of compound. As liquisolid compacts demonstrated significantly higher drug release rates, we lead to conclusion that it could be a promising strategy in improving the dissolution of poor water soluble drugs and formulating immediate .. Aqueous formulations using typical polymers to In regards to the second concept, i.e., the rectal delivery of antivial drugs, accommodation of either water soluble or insoluble drug candidates was considered relative to bioavailability. - The nature of information, a formulation should have or would like to have. Four placebo formulations were designed with a wide range of hydrophilic characteristics (aqueous to lipid) and rheological properties (Newtonian, shear thinning, thermal sensitive and thixotropic). 197–210, Churchill Livingstone, Longman group, Edinburg, UK, 2nd edition, 2002. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues. Chemical Stability of Pharmaceuticals (Second Edition), John Wiley & Sons, Inc., 1986. - The physicochemical properties of the drug already known.